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UMR 1332 Biologie du Fruit et Pathologie

Cécile Brès (Dr)

Cécile Brès
Research engineer - Management of the TILLING plateform
CV :
  • Date of birth : 12/04/1971
  • CURSUS :
    Post-graduate: "Genetic Resources and Plant breeding", University Paris XI / INA-PG. (1995)
    PhD: “Biology, Diversity and Adaptation of Cultivated Plants, National Superior School of Agronomy of Montpellier (ENSAM). (1996-2000)
    Post-doctorate (2003 to 2005) “Physical and functional mapping of resistance genes in potato. Genetic breeding of fruits and legumes insitute, INRA, Avignon, France
    Post-doctorate (2001 to 2003) “Positionnal cloning of DMI3, a gene involved in nodulation and myccorhization in Medicago truncatula” Plant-microorganism interaction institute, UMR INRA-CNRS 2495, Toulouse, France
    Post-doctorate (2000 to 2001) “Hybridisation between cultivated wheat and wild relatives (Aegilops ssp.) in France. Fertility restoration via amphiploidy, homeologous recombination” Laboratory of Plant Breeding, INRA, Montpellier, France

Cécile Bres
UMR 1332 BFP, Equipe Génomique Fonctionnelle du développement du fruit
Tel : +33 5 57 12 25 45
Fax : +33 5 57 12 25 41


Management of the TILLING plateform

GFDF group (Dir C Rothan) of UMR 1332 (Dir T Candresse) has developed a new approach of mutation identification in tomato. This approach has been developed by S. Henikoff group to discover new Arabidopsis mutants in known genes. TILLING (Targeting Induced Local Lesions IN Genomes) is a strategy of reverse genetic that combines the high density of point mutations provided by traditional chemical mutagenesis with rapid mutational screening to discover induced lesions.

Two EMS mutant populations have been developed in Microtom, a model genotype of small size and could be screened to search mutants, a first of 3500 M2 phenotyped families and a second of 4000 M2 families.

I am in charge of the plateform TILLING, which is a component of the “Plateforme Génome-Transcriptome” (Dir R Petit) from “Centre de Génomique Fonctionnelle de Bordeaux” (Dir C Rolin).

Research program

Map-based cloning of genes involved in cuticule formation and early fruit developpement


Number of publications in peer-reviewed journals :

Okabe Y, Asamizu E, Saito T, C., Matsukura C, Ariizumi T, Bres C, Rothan C, Mizoguchi T, Ezura H. 2011. Tomato TILLING technology: development of a reverse genetics tool for the efficient isolation of mutants from Micro-Tom mutant libraries. Plant and cell physiology. 52: 1994-2005.

Levy J*, Bres C*, Geurts R, Chalhoub B, Kulikova O, Duc G, Journet EP, Ane JM, Lauber E, Bisseling T, Denarie J, Rosenberg C, Debelle F. 2004. A putative Ca2+ and calmodulin-dependent protein kinase required for bacterial and fungal symbioses. Science. 303 : 1361-1364. *co-auteurs

David JL, Benavente E, Bres-Patry C, Dusautoir JC, Echaide M. 2004. Are neopolyploids a likely route for a transgene walk in the wild? The Aegilops ovata x Triticum durum case. The Biological Journal of The Linnean Society. 82,4 : 503 – 510

Bres-Patry C, Lorieux M, Clément G, Bangratz M, Ghesquière A, 2001. Heredity and mapping of domestication traits in temperate japonica weedy rice. Theoretical and Applied Genetics. 102 : 118-126

Bres-Patry C, Bangratz M, Ghesquière A, 2001. Genetic diversity and population dynamics of weedy rice in Camargue area. Genetics Selection Evolution. 33 : 425-440

Brevet :

Bres-Patry C, Debellé F, Levy J, Rosenberg C. A CCaMK involve in nodulation and endomycorrhization. 04290107.4 15.01.2004 EP Brevet européen déposé par VIALLE-PRESLES, Marie, José et al.

  • Hygiene and Safety Manager for UMR 619. 2006-present.
  • Elected Member of « conseil de gestion de l’UMR 619 » 2007-2011
  • Member named of « conseil de gestion du département Biologie Végétale » 2011-present
  • Membrer named of « commission d’évaluation des ingénieurs de l’INRA » 2012-present